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Sunday sees the initial Wear-Tyne derby since 2024, but who will emerge victorious – the Black Cats or the Magpies?
"During the bulk of last season, you couldn't have imagined the Wearside club getting promoted and being competitive with Eddie Howe's Newcastle, never mind being above them in the table," commented football expert Chris Sutton.
"The situation is very different now, and the way they play convinces me they've got a solid shot."
The analyst is providing scoreline guesses for all 380 Premier League games this season, against artificial intelligence, the public and a variety of guests.
For week 16, he is challenged by England Gaming star Daniel 'Stingray' Ray.
Ray is going for glory for the England's esports team – the Football Association's formal esports team – at the EA Sports FC European esports championship finals tournament, which takes place at Twickenham Stadium on Saturday.
You can watch Uefa's YouTube, IG Live and short-form video channels, as well as the official Twitch channel and its YouTube counterpart and the national team's Twitch.
Are you in alignment with their scores? Share your own guesses below.
The most popular scoreline chosen for each game is used in the leaderboards at the end of this page.
Predicting the right outcome (selecting a win, draw or defeat) is worth 10 points. A perfect prediction earns 40 points.
Ray, who competes for his club side and the Premier League champions as well as England, is making his debut at the eEuros finals after passing the qualifying.
The final eight competitors will play for their countries at the finals in a straight knockout, competing for a six-figure prize fund and a coveted spot in the FC Pro World Championship Play-Ins, with Denmark's Anders Vejrgang defending the title he won last year.
"My mindset is really good for it," Ray stated. "I've got a really good coach alongside me and practice has been going well.
"It is invariably an honour to play for your country. Obviously when you are younger, you dream about doing it as an actual footballer, but when you go into this field and there is an opportunity to represent England, donning the national jersey is something special.
"I defeated Vejrgang 9-4 in qualifying to get here. I've played against him over the course of the season just in practice, and in other tournaments before - but I'd not previously defeated him in a tournament before.
"I believe he is the top competitor in the world so getting a win over him in a tournament like this just delivers a huge surge of confidence."
Premier League Weekend Preview
Saturday, 13 December
Chelsea vs Everton
Stamford Bridge, 15:00 GMT
The London club were excellent against Arsenal at the end of November, when they got a draw after being reduced to 10 men, and I was thinking they've turned a corner, they could potentially be title contenders.
Since then, however, they were overpowered by Leeds, looked flat against Bournemouth and this week got defeated by Atalanta in the Champions League.
So manager Enzo Maresca desperately requires a win here to return to winning ways, but it will be a challenge because Everton are such a potent team.
Kiernan Dewsbury-Hall and Iliman Ndiaye are playing exceptionally and Everton have got a bit of a positive run at the moment.
Based on recent performances you would likely back the visitors, while the most prudent prediction would probably be a draw, but I'm going against logic.
Chelsea haven't given me any compelling evidence to back them recently, but I just have a gut instinct they will take this one because they are at home and they are due a win.
Sutton's prediction: 2-1
Stingray's prediction: With this being at the Bridge, I am going to back Chelsea. I think they will start off really well and go 2-0 up, then Everton will nick one back but then Chelsea score late. 3-1
AI's prediction: 2-0
Liverpool vs Brighton
Anfield, 15:00 GMT
I am at this game and it will be fascinating to see what we get from the Reds.
I am really pleased for Reds boss Arne Slot to get such a great win at Inter Milan on Tuesday after all the stuff with Mohamed Salah this week.
Slot ought not to put up with that drama. I know Salah has been a great for Liverpool but fundamentally Slot just wants to win games and there is nothing personal in his team selection.
Liverpool changed their tactical setup against Inter and went with a midfield diamond formation and two up top.
Everyone is going to be talking about whether Salah is selected for this game, but the only way he is going to be brought back into the fold is if he makes amends.
Slot's focus will be on winning this game, but it is a challenging encounter.
It's fair to say it is the same for most teams but I find Brighton so mercurial. I always feel they have got a goal in them, but they are defensively susceptible too.
The Merseysiders need to get back to a consistent run of form, but I am not sure how much their efforts at the San Siro will have affected their stamina.
I've selected a couple of Brighton players in my Fantasy Premier League side, so they will likely do poorly - but I do think they can get something at Anfield.
Sutton's prediction: 2-2
Stingray's prediction: This is a game which is going to give Liverpool a bit more of their confidence back. Obviously they had a good win in midweek and they can build more momentum here. 2-1
AI's prediction: 3-1
Sunday, 14 December
Sunderland vs Newcastle
Stadium of Light, 14:00 GMT
The Wearside club have had the week off while Newcastle had to work so hard against Bayer Leverkusen on Wednesday, only to let their lead slip away late on.
With the exception of their superb performance against Everton a couple of weeks ago, Newcastle's away form has been poor, particularly straight after they've played in the Champions League.
It is anticipated that that trend to continue on Sunday, and their lack of freshness is likely to be a factor in how this game goes because of their rivals' energetic style.
We saw how incessant Regis le Bris's side are. They dominated the Gunners, and it was amazing to watch.
Everyone talks about how Granit Xhaka has been brilliant for the Black Cats, and he has been excellent, but Noah Sadiki, who plays next to him, has also been one of the signings of the season and should be recognised too.
I am expecting this being the best game|most exciting fixture